MovDisordV3, Main, Exploration, bibRecord, 003C66

Long‐term follow‐up of cervical dystonia patients treated with botulinum toxin A

Identifieur interne : 003C66 ( Main/Exploration ); précédent : 003C65; suivant : 003C67

Long‐term follow‐up of cervical dystonia patients treated with botulinum toxin A

Auteurs : Peter Haussermann [Allemagne] ; Stefanie Marczoch [Allemagne] ; Christiane Klinger [Allemagne] ; Michael Landgrebe [Allemagne] ; Bastian Conrad [Allemagne] ; Andres Ceballos-Baumann [Allemagne]

Source :

Movement Disorders [ 0885-3185 ] ; 2004-03.

RBID : ISTEX:3CA93C260476B083610E6EDB3C10B059DB4C6FEC

Descripteurs français

Pascal (Inist)
- Bontoxilysin, Dystonie, Homme, Système nerveux pathologie.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Adult, Bontoxilysin, Botulinum Toxins, Type A (adverse effects), Botulinum Toxins, Type A (therapeutic use), Cohort Studies, Dystonia, Dystonic Disorders (chemically induced), Female, Follow-Up Studies, Human, Humans, Male, Meige Syndrome (chemically induced), Middle Aged, Nervous system diseases, Neuromuscular Agents (adverse effects), Neuromuscular Agents (therapeutic use), Quality of Life, Questionnaires, Time Factors, Torticollis (drug therapy), Torticollis (epidemiology), botulinum toxin A, cervical dystonia, long‐term outcome.
MESH :
- chemical , adverse effects : Botulinum Toxins, Type A, Neuromuscular Agents.
- chemical , therapeutic use : Botulinum Toxins, Type A, Neuromuscular Agents.
- chemically induced : Dystonic Disorders, Meige Syndrome.
- drug therapy : Torticollis.
- epidemiology : Torticollis.
- Adult, Cohort Studies, Female, Follow-Up Studies, Humans, Male, Middle Aged, Quality of Life, Questionnaires, Time Factors.

Abstract

We followed the course in 100 consecutive patients with cervical dystonia (CD) after they were initially treated with botulinum toxin (BTX) in the form of Dysport 10 to 12 years ago. A total of 4 patients had died, and 6 were lost to follow‐up. Of the remaining 90 patients, 57 (63%) were still treated with BTX. In the patients treated at one centre over the whole period with Dysport, mean dose used during each treatment session was 833 (SD ± 339) units Dysport with a cumulative dose of 20,943 (SD ± 9462) units Dysport over a mean of 26.8 (SD ± 8.6) treatment cycles. Secondary nonresponse was detected in 3 of the 90 patients. During follow‐up, 12 patients developed blepharospasm, 13 oromandibular dystonia, and 17 patients writer's cramp. We conclude that BTX remains effective and safe for approximately 60% of CD patients for more than 10 years. © 2003 Movement Disorder Society

Url:

https://api.istex.fr/document/3CA93C260476B083610E6EDB3C10B059DB4C6FEC/fulltext/pdf

DOI: 10.1002/mds.10659

Affiliations:

Le document en format XML

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<term>Time Factors</term>
<term>Torticollis (drug therapy)</term>
<term>Torticollis (epidemiology)</term>
<term>botulinum toxin A</term>
<term>cervical dystonia</term>
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<term>Cohort Studies</term>
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<term>Follow-Up Studies</term>
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<front><div type="abstract" xml:lang="en">We followed the course in 100 consecutive patients with cervical dystonia (CD) after they were initially treated with botulinum toxin (BTX) in the form of Dysport 10 to 12 years ago. A total of 4 patients had died, and 6 were lost to follow‐up. Of the remaining 90 patients, 57 (63%) were still treated with BTX. In the patients treated at one centre over the whole period with Dysport, mean dose used during each treatment session was 833 (SD ± 339) units Dysport with a cumulative dose of 20,943 (SD ± 9462) units Dysport over a mean of 26.8 (SD ± 8.6) treatment cycles. Secondary nonresponse was detected in 3 of the 90 patients. During follow‐up, 12 patients developed blepharospasm, 13 oromandibular dystonia, and 17 patients writer's cramp. We conclude that BTX remains effective and safe for approximately 60% of CD patients for more than 10 years. © 2003 Movement Disorder Society</div>
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Movement Disorders (revue)

Long‐term follow‐up of cervical dystonia patients treated with botulinum toxin A

Long‐term follow‐up of cervical dystonia patients treated with botulinum toxin A

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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